Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial.
We conducted a randomized, double-blind, placebo-controlled clinical trial to explore how magnesium treatments influence kidney stones, specifically for those with high levels of oxalate in their urine. Our study involved 90 participants with a history of calcium kidney stones, all of whom were experiencing idiopathic hyperoxaluria. They were divided into three groups receiving either magnesium oxide (MgO), magnesium citrate (MgCit), or a placebo for eight weeks, while their diets were monitored to keep nutritional intake consistent.
After the treatment period, we observed promising results. Both MgO and MgCit effectively reduced the excretion of oxalate in urine, which is a key factor in kidney stone formation. The Group taking magnesium citrate showed even more significant reductions in both oxalate levels and the calcium oxalate supersaturation index, which measures the concentration of stone-forming minerals in urine. This was notably true for participants with normal magnesium levels.
Overall, we found that magnesium supplements might play a beneficial role in decreasing critical risk factors for kidney stones, especially for those using magnesium citrate. It's encouraging to see that this may offer a practical option for those struggling with recurrent stones due to high oxalate excretion.
Read More
8
Dietary magnesium may reduce stones
Dietary Magnesium Intake and Kidney Stone: The National Health and Nutrition Examination Survey 2011-2018.
We wanted to understand the relationship between dietary magnesium intake and the prevalence of kidney stones. By examining data from the National Health and Nutrition Examination Survey spanning 2011 to 2018, we were able to analyze the self-reported history of kidney stones among participants.
Our findings indicated that those who consumed higher amounts of magnesium appeared to have a lower likelihood of experiencing kidney stones. Specifically, the average daily magnesium intake was lower in individuals with kidney stones, suggesting that magnesium might play a role in kidney stone formation.
In our analysis, we discovered that when grouped into different levels of magnesium intake, those in the highest intake category had significantly reduced odds of developing kidney stones compared to those in the lowest intake category. This trend suggests a protective effect of dietary magnesium against kidney stone disease.
While our results are promising, we recognize that further research is needed to determine if there is a direct causal relationship between magnesium intake and kidney stones. The evidence points towards a beneficial link, but more prospective studies will help clarify this important topic for better health outcomes.
Read More
3
Magnesium affects urine, not stones
Magnesium Decreases Urine Supersaturation but Not Calcium Oxalate Stone Formation in Genetic Hypercalciuric Stone-Forming Rats.
We explored the effects of magnesium on kidney stones, focusing specifically on how it might influence urinary chemistry and calcium oxalate (CaOx) stone formation. Using genetic hypercalciuric stone-forming rats, we divided the animals into three groups, each receiving different levels of magnesium for six weeks.
After analyzing the 24-hour urine collection, we observed notable changes depending on magnesium intake. Those on a low magnesium diet had higher urinary supersaturation levels of CaOx, while the high magnesium group showed a significant decrease in urinary supersaturation. However, we need to stress that despite these changes in urine chemistry, magnesium did not impact the actual formation of calcium oxalate stones within the study period.
In summary, while increasing dietary magnesium can lower supersaturation in urine, it doesn't appear to prevent the formation of calcium oxalate stones in this rat model. This finding is important for understanding the role of magnesium in kidney stone prevention.
Read More
Most Useful Reviews
9
Keeps stones away
Easy to swallow and fits well on my shelf where I store my vitamins. I really appreciate the attractive bottle design. This product is of good quality and keeps kidney stones away! I’ve used it for years, and it aids in numerous ways: it alleviates muscle cramps in my legs and toes and helps regulate essential bodily functions. Our bodies utilise this mineral effectively.
Read More
9
Boosts energy significantly
Magnesium malate was prescribed for my adrenal glands and kidney sands. I can’t comment on the adrenal glands, but it provides a massive energy boost and significantly alleviates restless legs syndrome after taking it. Absolutely YES!!!
Read More
7.5
Suitable for stones
Malate is suitable for individuals with sand in the kidneys. If you take magnesium consistently, alternate between different forms.
Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial.
We conducted a randomized, double-blind, placebo-controlled clinical trial to explore how magnesium treatments influence kidney stones, specifically for those with high levels of oxalate in their urine. Our study involved 90 participants with a history of calcium kidney stones, all of whom were experiencing idiopathic hyperoxaluria. They were divided into three groups receiving either magnesium oxide (MgO), magnesium citrate (MgCit), or a placebo for eight weeks, while their diets were monitored to keep nutritional intake consistent.
After the treatment period, we observed promising results. Both MgO and MgCit effectively reduced the excretion of oxalate in urine, which is a key factor in kidney stone formation. The Group taking magnesium citrate showed even more significant reductions in both oxalate levels and the calcium oxalate supersaturation index, which measures the concentration of stone-forming minerals in urine. This was notably true for participants with normal magnesium levels.
Overall, we found that magnesium supplements might play a beneficial role in decreasing critical risk factors for kidney stones, especially for those using magnesium citrate. It's encouraging to see that this may offer a practical option for those struggling with recurrent stones due to high oxalate excretion.
Read More
8
Magnesium's complex role in kidney stones
Machine Learning Models Decoding the Association Between Urinary Stone Diseases and Metabolic Urinary Profiles.
We analyzed how magnesium levels in urine might influence the occurrence of kidney stones. The study involved a mix of 468 patients who had been diagnosed with various types of urinary stones and underwent a detailed 24-hour urine analysis.
Our investigation found that 24-hour urinary magnesium was positively associated with both kidney stones and stones in multiple locations. Specifically, higher levels of magnesium corresponded with increased risk for these conditions. This relationship was particularly interesting because magnesium was highly correlated with another mineral, urinary phosphorus.
On the flip side, we also identified that 24-hour urinary creatinine acted as a protective factor against kidney and ureter stones, suggesting that maintaining adequate creatinine levels could potentially help prevent these types of stones. Additionally, eGFR (estimated Glomerular Filtration Rate) was noted as a risk factor especially for ureter stones and those that appear in multiple locations.
Ultimately, our study underscores that while magnesium is linked to stone formation, there are other contributing factors at play as well. This knowledge could guide improvements in dietary or medicinal strategies aimed at preventing kidney stones, especially emphasizing the need for a balanced intake of minerals in our diets.
Read More
8
Magnesium's role in kidney stones
Oral supplementation with probiotics, potassium citrate, and magnesium in reducing crystalluria in stone formers: A phase II study.
We analyzed a study focused on the effects of a combination of probiotics, potassium, and magnesium on kidney stone formation, specifically looking at crystalluria, which is the presence of crystals in urine that can signal the recurrence of kidney stones. The study involved 23 patients with calcium oxalate kidney stones who had crystalluria but normal metabolic profiles.
Over the course of 20 days, the patients received daily supplementation with beneficial bacteria, including Lactobacillus paracasei, Lactobacillus plantarum, and Bifidobacterium breve, along with potassium citrate and magnesium. After treatment, we observed a decrease in the presence of crystalluria at multiple follow-up points—1, 3, 6, and 12 months later.
Interestingly, while we noted that the probiotics and other agents helped reduce crystalluria, the study did not isolate the specific effects of magnesium alone. Therefore, we must be cautious in drawing firm conclusions about magnesium’s standalone effectiveness in this context.
Overall, the findings suggest that combining these supplements can be beneficial for patients with kidney stones, but the role of magnesium specifically requires further investigation.
Read More
8
Magnesium improves urine levels
Magnesium Supplementation Increases Urine Magnesium and Citrate in Stone Formers With Hypomagnesuria.
We aimed to find out how magnesium affects urinary levels of magnesium and citrate in people who form kidney stones and have low magnesium in their urine. By examining medical records, we compared two approaches: one group increased their magnesium through foods, while the other group received magnesium supplements.
We focused on adult patients whose urine magnesium levels were less than 70 mg a day. Following our recommendations, we observed significant changes after both dietary increases and supplementation. Those who took magnesium supplements showed a more pronounced improvement—about 88% were able to raise their urine magnesium to at least 70 mg a day, compared to just 58% in the dietary group.
Interestingly, only the supplement group showed a noticeable increase in urine citrate levels, which is also crucial in the prevention of kidney stones. Overall, both dietary and supplemental magnesium effectively improved magnesium levels, but supplementation had greater success in achieving desirable levels.
Read More
8
Dietary magnesium may reduce stones
Dietary Magnesium Intake and Kidney Stone: The National Health and Nutrition Examination Survey 2011-2018.
We wanted to understand the relationship between dietary magnesium intake and the prevalence of kidney stones. By examining data from the National Health and Nutrition Examination Survey spanning 2011 to 2018, we were able to analyze the self-reported history of kidney stones among participants.
Our findings indicated that those who consumed higher amounts of magnesium appeared to have a lower likelihood of experiencing kidney stones. Specifically, the average daily magnesium intake was lower in individuals with kidney stones, suggesting that magnesium might play a role in kidney stone formation.
In our analysis, we discovered that when grouped into different levels of magnesium intake, those in the highest intake category had significantly reduced odds of developing kidney stones compared to those in the lowest intake category. This trend suggests a protective effect of dietary magnesium against kidney stone disease.
While our results are promising, we recognize that further research is needed to determine if there is a direct causal relationship between magnesium intake and kidney stones. The evidence points towards a beneficial link, but more prospective studies will help clarify this important topic for better health outcomes.
Easy to swallow and fits well on my shelf where I store my vitamins. I really appreciate the attractive bottle design. This product is of good quality and keeps kidney stones away! I’ve used it for years, and it aids in numerous ways: it alleviates muscle cramps in my legs and toes and helps regulate essential bodily functions. Our bodies utilise this mineral effectively.
Read More
9
Boosts energy significantly
Magnesium malate was prescribed for my adrenal glands and kidney sands. I can’t comment on the adrenal glands, but it provides a massive energy boost and significantly alleviates restless legs syndrome after taking it. Absolutely YES!!!
Read More
7.5
Suitable for stones
Malate is suitable for individuals with sand in the kidneys. If you take magnesium consistently, alternate between different forms.
Read More
7.5
Aids muscle function
Excellent! I have been taking Magnesium Malate NOW 1000 mg tablets for some time, as prescribed by my gynecologist. I choose this brand because it contains no harmful components, and their reputation in the dietary supplements market is well established. I try to take magnesium at least annually. It plays a vital role in muscle function and biochemical processes. In our stressful times, everyone should ensure they have magnesium, especially when taking vitamin D to prevent stone formation. I find the malate form invigorating and it’s well absorbed.
Read More
Frequently Asked Questions
Kidney stones are hard deposits made of minerals and salts that form inside your kidneys. While they can vary in size from tiny particles to large stones, they all begin as crystallized substances that develop when urine contains more crystal-forming substances than the fluid in your urine can dilute. When the crystals stick together, they can form stones, which may cause severe pain, especially when they pass through the urinary tract. Common types of kidney stones include calcium stones, struvite stones, uric acid stones, and cystine stones.
The symptoms of kidney stones can include sharp pain in the side and back, pain during urination, pink or red urine, and frequent urination. Various factors can increase the risk of developing kidney stones, including dehydration, certain dietary choices, and genetic predisposition. Preventing kidney stones often involves drinking plenty of water, avoiding excessive salt and animal protein, and ensuring a balanced intake of calcium. For those who suffer from kidney stones, a medical evaluation may be necessary to determine the best management and preventive strategies.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium may play a supportive role in the prevention of kidney stones, particularly calcium oxalate stones, which are the most common type. Research suggests that adequate magnesium intake can help inhibit the crystallization of calcium oxalate in the kidneys. Magnesium works by binding to oxalate, which can reduce the amount of oxalate available to form stones. This process could potentially decrease the likelihood of developing kidney stones in individuals who are prone to them.
However, it's important to note that while magnesium may help, it should not be viewed as a standalone solution for kidney stone prevention or treatment. A well-rounded approach that includes staying hydrated, managing dietary oxalate intake, maintaining appropriate calcium levels, and consulting healthcare professionals for personalized advice remains crucial. If you have a history of kidney stones or are concerned about your risk, it's best to discuss magnesium supplementation and dietary changes with your doctor to determine the most effective and safe strategy for your specific situation.
Based on user reviews, the timeline for noticing results from taking magnesium supplements for kidney stones can vary. Some users indicate that they have used the supplements consistently for years and have found them effective in keeping kidney stones away and alleviating other conditions, which suggests a long-term commitment might be necessary to observe significant benefits Read Review. Others highlight immediate effects, such as increased energy and relief from symptoms like restless legs syndrome shortly after starting the regimen Read Review.
Overall, while some individuals report noticeable improvements in their conditions relatively quickly, particularly with regular intake Read Review, others imply that maintaining a long-term supplement routine is crucial for preventing kidney stones effectively Read Review. Thus, patience and regular intake of magnesium supplements appear to be key to achieving desired results.
The scientific research surrounding the role of magnesium in preventing kidney stones presents a nuanced picture. Several studies indicate that higher magnesium intake can correlate with a reduced risk of developing kidney stones. For instance, research involving adults over 50 revealed that those consuming larger amounts of magnesium exhibited lower odds of experiencing kidney stones, particularly in women ([3]). On the other hand, a study focused on the relationship between urinary magnesium levels and stone formation found that higher urinary magnesium was associated with an increased risk of certain types of kidney stones, which complicates the narrative ([2]).
Additionally, clinical trials have shown that magnesium supplementation, especially in forms like magnesium citrate, can help lower oxalate excretion, thereby reducing a significant risk factor for kidney stones ([5]). Other studies have reported that magnesium supplementation significantly raises urinary magnesium and citrate levels—two factors that are crucial in preventing kidney stones ([6]). Overall, while there is promising evidence suggesting that magnesium may aid in kidney stone prevention, it is crucial to approach the findings with an understanding that not all studies agree and more prospective research is needed to clarify these relationships clearly.
Based on user reviews, many individuals have reported significant improvements in various symptoms after incorporating magnesium supplements into their routine. For instance, one user noted that after taking the supplement, they experienced a substantial energy boost and relief from restless legs syndrome, highlighting the immediate benefits Read Review. Another user mentioned that consistent use over the years has not only helped in keeping kidney stones at bay but also alleviated muscle cramps, allowing them to function more effectively Read Review.
Additional feedback suggests that consistent intake of magnesium, particularly in the malate form, may enhance absorption and overall efficacy in managing related health issues. Users emphasize the importance of maintaining a regular supplementation routine, with some reporting that alternating between different forms is beneficial for optimal results Read Review. Overall, while individual results can vary, the positive experiences shared suggest that magnesium supplements may offer valuable support for muscle function and energy levels.
Users have shared a variety of experiences regarding the combination of magnesium supplements for managing kidney stones alongside other supplements. Many report positive outcomes when using magnesium malate, especially when taken consistently. One user emphasized the importance of alternating different forms of magnesium for optimal results, stating that malate is particularly effective for those with kidney sand, hinting at beneficial synergies in managing urinary health Read Review. Others noted that incorporating magnesium into their routine, especially alongside vitamin D, is essential for preventing kidney stone formation Read Review.
Moreover, users highlighted the various health benefits related to magnesium supplementation, ranging from energy boost to alleviating issues like restless legs syndrome. One individual specifically credited magnesium malate for improving energy levels and managing discomfort associated with kidney stones and sands Read Review. Overall, these user insights suggest that combining magnesium supplements with other vitamins and maintaining a varied intake can enhance their effectiveness in managing kidney health.
The optimal dose of magnesium for reducing the risk of kidney stones appears to be around 350 mg per day. Research indicates that individuals who consume this amount experience lower odds of developing kidney stones, with the protective effects of magnesium plateauing beyond this threshold [3]. This is especially relevant for women over the age of 50, who show a significant inverse relationship with magnesium intake and kidney stone development.
It's important to note that while higher levels of magnesium in water have been associated with a decreased risk of kidney stones, the relationship is complex. Factors like age, sex, and overall dietary habits can influence this outcome [1], and there is evidence that higher urinary magnesium levels may actually correlate with increased stone risk [2]. Thus, a balanced and mindful approach to magnesium intake is crucial for those concerned about kidney stones.
9
Keeps stones away
Easy to swallow and fits well on my shelf where I store my vitamins. I really appreciate the attractive bottle design. This product is of good quality and keeps kidney stones away! I’ve used it for years, and it aids in numerous ways: it alleviates muscle cramps in my legs and toes and helps regulate essential bodily functions. Our bodies utilise this mineral effectively.
9
Boosts energy significantly
Magnesium malate was prescribed for my adrenal glands and kidney sands. I can’t comment on the adrenal glands, but it provides a massive energy boost and significantly alleviates restless legs syndrome after taking it. Absolutely YES!!!
7.5
Suitable for stones
Malate is suitable for individuals with sand in the kidneys. If you take magnesium consistently, alternate between different forms.
7.5
Aids muscle function
Excellent! I have been taking Magnesium Malate NOW 1000 mg tablets for some time, as prescribed by my gynecologist. I choose this brand because it contains no harmful components, and their reputation in the dietary supplements market is well established. I try to take magnesium at least annually. It plays a vital role in muscle function and biochemical processes. In our stressful times, everyone should ensure they have magnesium, especially when taking vitamin D to prevent stone formation. I find the malate form invigorating and it’s well absorbed.
7
Magnesium reduces kidney stone risk
Association Between Magnesium Intake and Chronic Kidney Diseases and Kidney Stones in Adults Aged 50 years and Older: Dose-Response Analysis of a Nationally Representative Population-Based Study.
We examined the relationship between magnesium intake and the risk of kidney stones in adults aged 50 and older. By analyzing data collected from the National Health and Nutrition Examination Survey spanning over a decade, we aimed to understand whether increasing magnesium levels could help reduce the chances of developing kidney stones.
Our findings revealed that there is indeed a noteworthy link between magnesium consumption and kidney stones. Specifically, we observed that individuals who consumed higher amounts of magnesium had lower odds of experiencing kidney stones. This trend was especially significant for women, who showed a clearer inverse relationship with magnesium intake.
Interestingly, our results indicated that the protective benefits of magnesium plateau around a daily intake of 350 mg. This means that while increasing magnesium consumption can lower the risk of kidney stones, beyond this threshold, additional magnesium may not yield further benefits.
Overall, our study sheds light on the potential role of magnesium in preventing kidney stones and emphasizes the importance of maintaining a balanced diet rich in this essential mineral for individuals over 50.
8
Magnesium's complex role in kidney stones
Machine Learning Models Decoding the Association Between Urinary Stone Diseases and Metabolic Urinary Profiles.
We analyzed how magnesium levels in urine might influence the occurrence of kidney stones. The study involved a mix of 468 patients who had been diagnosed with various types of urinary stones and underwent a detailed 24-hour urine analysis.
Our investigation found that 24-hour urinary magnesium was positively associated with both kidney stones and stones in multiple locations. Specifically, higher levels of magnesium corresponded with increased risk for these conditions. This relationship was particularly interesting because magnesium was highly correlated with another mineral, urinary phosphorus.
On the flip side, we also identified that 24-hour urinary creatinine acted as a protective factor against kidney and ureter stones, suggesting that maintaining adequate creatinine levels could potentially help prevent these types of stones. Additionally, eGFR (estimated Glomerular Filtration Rate) was noted as a risk factor especially for ureter stones and those that appear in multiple locations.
Ultimately, our study underscores that while magnesium is linked to stone formation, there are other contributing factors at play as well. This knowledge could guide improvements in dietary or medicinal strategies aimed at preventing kidney stones, especially emphasizing the need for a balanced intake of minerals in our diets.
9
Magnesium reduces kidney stone risk
Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial.
We conducted a randomized, double-blind, placebo-controlled clinical trial to explore how magnesium treatments influence kidney stones, specifically for those with high levels of oxalate in their urine. Our study involved 90 participants with a history of calcium kidney stones, all of whom were experiencing idiopathic hyperoxaluria. They were divided into three groups receiving either magnesium oxide (MgO), magnesium citrate (MgCit), or a placebo for eight weeks, while their diets were monitored to keep nutritional intake consistent.
After the treatment period, we observed promising results. Both MgO and MgCit effectively reduced the excretion of oxalate in urine, which is a key factor in kidney stone formation. The Group taking magnesium citrate showed even more significant reductions in both oxalate levels and the calcium oxalate supersaturation index, which measures the concentration of stone-forming minerals in urine. This was notably true for participants with normal magnesium levels.
Overall, we found that magnesium supplements might play a beneficial role in decreasing critical risk factors for kidney stones, especially for those using magnesium citrate. It's encouraging to see that this may offer a practical option for those struggling with recurrent stones due to high oxalate excretion.
8
Magnesium improves urine levels
Magnesium Supplementation Increases Urine Magnesium and Citrate in Stone Formers With Hypomagnesuria.
We aimed to find out how magnesium affects urinary levels of magnesium and citrate in people who form kidney stones and have low magnesium in their urine. By examining medical records, we compared two approaches: one group increased their magnesium through foods, while the other group received magnesium supplements.
We focused on adult patients whose urine magnesium levels were less than 70 mg a day. Following our recommendations, we observed significant changes after both dietary increases and supplementation. Those who took magnesium supplements showed a more pronounced improvement—about 88% were able to raise their urine magnesium to at least 70 mg a day, compared to just 58% in the dietary group.
Interestingly, only the supplement group showed a noticeable increase in urine citrate levels, which is also crucial in the prevention of kidney stones. Overall, both dietary and supplemental magnesium effectively improved magnesium levels, but supplementation had greater success in achieving desirable levels.
7
Magnesium's protective role uncertain
The association between domestic water hardness and kidney stone disease: a prospective cohort study from the UK Biobank.
We investigated how magnesium levels in domestic water may affect the risk of kidney stones, a common and painful health issue. This study followed 288,041 participants in the UK Biobank who had no previous history of kidney stones, gathering data over an 18-year period from 2006 to 2024.
Our findings highlighted an interesting relationship between magnesium and kidney stones. We observed that higher magnesium levels in water could actually lower the risk of developing these stones, particularly in younger men and those without kidney issues. However, for the broader population, domestic water hardness and calcium concentrations did not seem to have a significant impact on kidney stone formation.
We also noted that participants over 60 years old and females were more susceptible to kidney stones in relation to hard water and its calcium content. This insight prompts a closer look at the role of minerals like magnesium and calcium in kidney stone prevention, particularly in different age groups and demographics. Overall, while magnesium appeared beneficial, our results underscore the complex nature of how various minerals interact and influence kidney stone risks.
References
Zhang J, Luo H, Wu H, Qian Y, Tang Z, et al. The association between domestic water hardness and kidney stone disease: a prospective cohort study from the UK Biobank. Int J Surg. 2025;111:1957. doi:10.1097/JS9.0000000000002198
Ma L, Qiao Y, Wang R, Chen H, Liu G, et al. Machine Learning Models Decoding the Association Between Urinary Stone Diseases and Metabolic Urinary Profiles. Metabolites. 2024;14. doi:10.3390/metabo14120674
Zhao H, Wang Y, Guan L, Sun Y. Association Between Magnesium Intake and Chronic Kidney Diseases and Kidney Stones in Adults Aged 50 years and Older: Dose-Response Analysis of a Nationally Representative Population-Based Study. J Ren Nutr. 2024. doi:10.1053/j.jrn.2024.11.004
Vittori M, Bove P, Signoretti M, Cipriani C, Gasparoli C, et al. Oral supplementation with probiotics, potassium citrate, and magnesium in reducing crystalluria in stone formers: A phase II study. Urologia. 2024;91:681. doi:10.1177/03915603241272146
Taheri M, Jalali S, Borumandnia N, Tavasoli S, Basiri A, et al. Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial. Magnes Res. 2024;37:12. doi:10.1684/mrh.2024.0524
Penniston KL, Coughlin MM, Jhagroo RA. Magnesium Supplementation Increases Urine Magnesium and Citrate in Stone Formers With Hypomagnesuria. J Ren Nutr. 2024. doi:10.1053/j.jrn.2024.06.002
Li Q, Krieger NS, Yang L, Asplin J, Bushinsky DA. Magnesium Decreases Urine Supersaturation but Not Calcium Oxalate Stone Formation in Genetic Hypercalciuric Stone-Forming Rats. Nephron. 2024;148:480. doi:10.1159/000534495
Shringi S, Raker CA, Tang J. Dietary Magnesium Intake and Kidney Stone: The National Health and Nutrition Examination Survey 2011-2018. R I Med J (2013). 2023;106:20.
Rodriguez-Hesles CA, Alkhatatbeh H, Alonso Bartolomé MB, Valladares Ferreiro CA, Ayllón Blanco HR, et al. Urine alkalinization for dissolution of uric acid stones and treatment of other urological diseases with a treatment combining potassium magnesium citrate and theobromine. Arch Ital Urol Androl. 2025;97:13824. doi:10.4081/aiua.2025.13824